Transcranial sonography and functional imaging in glucocerebrosidase mutation Parkinson disease
نویسندگان
چکیده
منابع مشابه
Transcranial sonography in the evaluation of Parkinson disease.
OBJECTIVE With transcranial sonography (TS), it is possible to visualize hyperechoic signals in the sub-stantia nigra (SN) in patients with Parkinson disease (PD). Our objective was to correlate the level of echogenicity in the SN with clinical status in patients with PD. METHODS In our pilot study, using TS, we examined 15 patients with the confirmed presence of PD. Staging of the latest cli...
متن کامل[Transcranial sonography for the diagnosis of Parkinson disease].
BACKGROUND The detection of hyperechogenicity of the substantia nigra using trans cranial sonography can be predictive of the diagnosis of Parkinson Disease. AIM To report an experience with transcranial sonography for the diagnosis of Parkinson disease. Material ana METHODS One hundred sixteen patients with movement disorders were subjected to a transcranial sonography to detect the presen...
متن کاملGlucocerebrosidase Mutations in Parkinson Disease.
Following the discovery of a higher than expected incidence of Parkinson Disease (PD) in Gaucher disease, a lysosomal storage disorder, mutations in the glucocerebrocidase (GBA) gene, which encodes a lysosomal enzyme involved in sphingolipid degradation were explored in the context of idiopathic PD. GBA mutations are now known to be the single largest risk factor for development of idiopathic P...
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BACKGROUND AND PURPOSE Nonimaging transcranial Doppler sonography (TCD) and imaging TCD (TCDI) are used for determination of the risk of stroke in children with sickle cell disease (SCD). The purpose was to compare angle-corrected, uncorrected TCDI, and TCD blood flow velocities in children with SCD. MATERIALS AND METHODS A total of 37 children (mean age, 7.8 +/- 3.0 years) without intracrani...
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Background: Parkinson's disease as a progressive disorder of the nervous system leads to the disability of postural control system. Objectives: In the present study the effects of Pilates exercises on functional balance in patients with Parkinson's was investigated. Materials and Methods: This control trial included 30 patients with idiopathic Parkinson's disease who were selected as subj...
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ژورنال
عنوان ژورنال: Parkinsonism & Related Disorders
سال: 2013
ISSN: 1353-8020
DOI: 10.1016/j.parkreldis.2012.09.007